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DNSCrypt is offered by OpenDNS
Domain Name System Security Extensions (DNSSEC) is a separate DNS security solution that authenticates DNS traffic. It modifies DNS to add support for cryptographically signed responses, thereby preventing the tampering of the IP addresses that are returned from the DNS server.
It may seem like DNSCrypt and DNSSEC are competing solutions, but they are actually complimentary and can be used together for comprehensive security. DNSSEC provides protection against DNS spoofing and other man-in-the-middle attacks, and DNSCrypt provides double-protection and prevents any eavesdropping on traffic, even by ISPs.
It even will be available for Microsoft in April.
This software seems to become more and more important given the eagerness from all sides to spy on you for all the "good" reasons in the world (Intellectual property etc.).
Remember those ISP's who volunteered to spy on you?
more here... and here